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04.12.2017

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Stiftung caesar
Lufwig-Erhard-Allee 2
53175 Bonn

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Bonn

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Rita Repschläger
0228 / 9656-106

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Ph.D. candidate (m/f) (background in biochemistry or biophysics)

04.10.2017
Stiftung caesar - Bonn
Biochemie

Aufgaben

The Department of Behavior and Brain Organization is looking for a

Ph.D. candidate (m/f) (background in biochemistry or biophysics)
the position is available immediately

Project description (Characterization of genetically encoded calcium indicators)
Fluorescence-based, genetically encoded calcium indicators have enabled the study of activity in large populations of neurons over time. In order to reliably infer synaptic activity or action potentials from the observed calcium transients, we have to understand the indicators response characteristics, like changes in fluorescence in response to changing calcium levels and the association and dissociation kinetics.

Qualifikation

Who are we looking for
The Ph.D. student should ideally have a solid background in protein biochemistry and/or biophysics and will be involved in the expression, purification and subsequent characterization of fluorescent calcium sensors. The candidate will use a number of biophysical techniques like fluorescence spectroscopy, isothermal titration calorimetry and fast kinetic approaches to determine the fluorescence changes of the indicator in response to calcium. The candidate will also design and optimize sensor constructs (mutagenesis, cloning, virus production) and work in close collaboration with colleagues in the department of Behavior and Brain Organization.

Benefits

Caesar is committed to diversity and inclusion and is aiming to increase the percentage of women in areas where they are under-represented. We therefore explicitly encourage women to apply.
Handicapped persons with comparable qualifications receive preferential status.

More information on the group can be found at our homepage.

Caesar is certified according to the audit berufundfamilie.

Weitere Angaben

Sprachkenntnisse: Englisch
Beginn:
Dauer: 3 Jahre
Vergütung:
Anzahl der Plätze: 1

Angaben zum Unternehmen

Unternehmensbeschreibung
Caesar is a Neuroscience research institute associated with the Max Planck Society and is located in Bonn, Germany. Caesar’s research is interdisciplinary with scientists from various research areas working together on the topics of cellular signal processing and the neural foundations of behavior. This ranges from studying the behavior of single-cell organisms to studying one of the key questions of neuroscience: how does neuronal activity give rise to complex and goal-directed behavior?

Unternehmensgröße
101-250 Mitarbeiter

Branchen
Forschung und Entwicklung im Bereich Biotechnologie

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